DNA Fragmentation, is a form of sperm damage and is a phenomenon associated with poor sperm fertilizing ability and the subsequent potentially problematic development of pregnancy. There is certainly a correlation between DNA fragmentation and a man’s ability to fertilize his partner’s eggs.
Simply it’ s quantification and laboratory detection is still in very early stages without being able to recognize the normal values in the general population of fertile men.with past years’ data. I personally use this test only to convince a man who smokes or drinks a lot of alcohol to change his lifestyle and not to suggest his genetic material replacement by a donor.
Obesity & Smoking
Obesity and smoking are now highly related to decreased sperm mobility and an increased rate of abnormal sperm counts as well as increased DNA Fragmentation index.